Publications

 

Interview of our accreditated nipt test on the Flemish T.V.: http://nieuws.vtm.be/binnenland/74035-veilige-test-voor-aanstaande-mamas (Dutch only).

 

Interview of supported Bioinformatics work on the Flemish T.V.: http://www.deredactie.be/permalink/1.1511169 (Dutch only).

 

Relevant Publications

Garcia-Dios DA, Lambrechts D, Coenegrachts L, Vandenput I, Capoen A, Webb PM, Ferguson K, Anecs, Akslen LA, Claes B, Vergote I, Moerman P, Van Robays J, Marcickiewicz J, Salvesen HB, Spurdle AB, Amant F
High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma
Gynecologic Oncology; 128; 2; 327-334, 2013 (IF=3.888; times cited=0)

Hennekam R, Vermeesch JR.
Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome.
Nat Genet. 2012 Feb 26;44(4):445-9, S1

Hollants S, Redeker EJ, Matthijs G.
Microfluidic amplification as a tool for massive parallel sequencing of the familial hypercholesterolemia genes.
Clin Chem. 2012 Apr;58(4):717-24. doi: 10.1373/clinchem.2011.173963. Epub 2012 Jan 31.

Lambrechts D, Buysschaert I, Zanen P, Coolen J, Lays N, Cuppens H, Groen H, Dewever W, van Klaveren R, Verschakelen J, Wijmenga C, Postma D, Decramer M, Janssens W
The 15q24/25 Susceptibility Variant for Lung Cancer and COPD is Associated with Emphysema
American Journal of Respiratory and Critical Care Medicine; 181; 5; 486-493, 2010 (IF=10.191; times cited=30)

Lambrechts D, Claes B, Delmar P, Reumers J, Mazzone M, Yesilyurt BT, Devlieger R, Verslype C, Tejpar S, Wildiers H, de Haas S, Carmeliet P, Scherer SJ, Van Cutsem E
VEGF pathway genetic varaints as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AviTA and AVOREN randomised trials
Lancet Oncology; 13; 7; 724-733, 2012 (IF=17.764; times cited=8)

Michils G, Hollants S, Dehaspe L, Van Houdt J, Bidet Y, Uhrhammer N, Bignon YJ, Vermeesch JR, Cuppens H, Matthijs G.
Molecular analysis of the breast cancer genes BRCA1 and BRCA2 using amplicon-based massive parallel pyrosequencing.
J Mol Diagn. 2012 Nov;14(6):623-30. doi: 10.1016/j.jmoldx.2012.05.006. Epub 2012 Sep 30.

Matthijs G, Rymen D, Millón MB, Souche E, Race V.
Approaches to homozygosity mapping and exome sequencing for the identification of novel types of CDG.
Glycoconj J. 2013 Jan;30(1):67-76. doi: 10.1007/s10719-012-9445-7. Epub 2012 Sep 15.

Reumers J, De Rijk P, Zhao H, Liekens A, Smeets D, Cleary J, Van Loo P, Van Den Bossche M, Catthoor K, Sabbe B, Despierre E, Vergote I, Hilbush B, Lambrechts D, Del-Favero J
Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing
Nature Biotechnology; 30; 1; 61-68, 2011 (IF=31.085; times cited=7)

Robberecht, C., Voet, T., Zamani Esteki, M., Nowakowska, B., Vermeesch, J.(2012).
Non−allelic homologous recombination between retrotransposable elements is a driver of de novo unbalanced translocations.
Genome Research, 2013  Ahead of print.

Vanneste E, Voet T, Le Caignec C, Ampe M, Konings P, Melotte C, Debrock S, Amyere M, Vikkula M, Schuit F, Fryns JP, Verbeke G, D'Hooghe T, Moreau Y, Vermeesch JR
Chromosome instability is common in human cleavage-stage embryos.
Nat Med. 2009 May;15(5):577-83.

Van Houdt JK, Nowakowska BA, Sousa SB, van Schaik BD, Seuntjens E, Avonce N, Sifrim A, Abdul-Rahman OA, van den Boogaard MJ, Bottani A, Castori M, Cormier-Daire V, Deardorff MA, Filges I, Fryer A, Fryns JP, Gana S, Garavelli L,  Gillessen-Kaesbach G, Hall BD, Horn D, Huylebroeck D, Klapecki J, Krajewska-Walasek M, Kuechler A, Lines MA, Maas S, Macdermot KD, McKee S, Magee A, de Man SA, Moreau Y, Morice-Picard F, Obersztyn E, Pilch J, Rosser E, Shannon  N, Stolte-Dijkstra I, Van Dijck P, Vilain C, Vogels A, Wakeling E, Wieczorek D, Wilson L, Zuffardi O, van Kampen AH, Devriendt K, Hennekam R, Vermeesch JR
Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome.
Nat Genet. 2012 Feb 26;44(4):445-9, S1

 

Own Publications

Van Houdt JK, Souche E, Herten K, Jackmaert S, Luyten E, Brys V, Dehaspe L and Vermeesch JR
High-throughput sample identification and tracking for exome and custom targeted sequencing projects
Genetics of Human Development EXPOsed. 2013 March 15, Belgian Society of Human Genetics
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Contact: genomicscore@uzleuven.be +32 16 33 08 21